Binding Kinetics in a Biosensor

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CFD-ACE+ CFD

Summary

This is a 3D model of chemical binding kinetics in a millimeter-scale biosensor. The objective of the model is to investigate the effects of various kinetic parameters on the simulated response. A general objective of modeling such problems (not covered here) could be to evaluate the effectiveness of the mathematical model for extracting kinetic parameters from the sensogram.

Detail

This tutorial will discuss the following topics:

  • Read the grid model into the GUI and set up the physical model.
  • Activate Chem module needed for binding kinetics modeling.
  • Specify transient solution process.
  • Specify model input parameters expected by the solver for binding kinetics.
  • Define volume and boundary conditions for binding kinetics.
  • Set initial conditions, solver parameters and run the solution.
  • Post-process the solution.

Download the file(s)

Download2014_ace_tut_008_Biosensor.zip 3.76 MB